Hyun-Soo Cho Selected Research

Histone Methyltransferases

9/2022	Epigenetic Silencing of CHOP Expression by the Histone Methyltransferase EHMT1 Regulates Apoptosis in Colorectal Cancer Cells.
11/2021	EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression.
1/2018	EHMT2 is a metastasis regulator in breast cancer.
2/2015	WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
2/2013	The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
12/2011	The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
10/2011	Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
7/2011	Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.

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Hyun-Soo Cho Research Topics

Disease

41	Neoplasms (Cancer) 11/2021 - 02/2003
9	Carcinogenesis 12/2015 - 02/2011
7	Lung Neoplasms (Lung Cancer) 01/2022 - 10/2011
6	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2006
5	Colorectal Neoplasms (Colorectal Cancer) 09/2022 - 02/2011
5	Breast Neoplasms (Breast Cancer) 01/2020 - 02/2003
4	Colonic Neoplasms (Colon Cancer) 01/2022 - 03/2019
4	Urinary Bladder Neoplasms (Bladder Cancer) 08/2013 - 05/2011
3	Inflammation (Inflammations) 05/2021 - 02/2006
3	Hypoxia (Hypoxemia) 12/2020 - 09/2019
3	Hepatocellular Carcinoma (Hepatoma) 09/2020 - 12/2017
3	Liver Neoplasms (Liver Cancer) 12/2017 - 11/2016
3	Obesity 06/2015 - 01/2010
3	Corneal dystrophy Avellino type 05/2010 - 07/2009
2	Adenocarcinoma 08/2021 - 01/2020
2	Necrosis 02/2019 - 01/2006
2	Alzheimer Disease (Alzheimer's Disease) 10/2018 - 02/2006
2	Sepsis (Septicemia) 01/2016 - 09/2011
2	Wolf-Hirschhorn Syndrome 02/2013 - 10/2011
2	Hereditary Corneal Dystrophies 04/2010 - 07/2009
1	Asthma (Bronchial Asthma) 01/2022
1	COVID-19 01/2022
1	Lung Diseases (Lung Disease) 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Chemical and Drug Induced Liver Injury 05/2021
1	Stomach Neoplasms (Stomach Cancer) 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2020
1	Bronchiolitis Obliterans Syndrome 01/2020
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020
1	Triple Negative Breast Neoplasms 01/2020
1	Body Weight (Weight, Body) 01/2020
1	Colitis 01/2020
1	Vasculitis (Vasculitides) 01/2020
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 12/2019
1	Melanoma (Melanoma, Malignant) 05/2019

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 12/2019 - 02/2006
8	Histone MethyltransferasesIBA 09/2022 - 07/2011
8	Pharmaceutical PreparationsIBA 12/2019 - 05/2011
7	Histones (Histone)IBA 09/2019 - 10/2011
7	Complementary DNA (cDNA)IBA 08/2012 - 04/2010
5	Histone DemethylasesIBA 08/2013 - 02/2011
4	Biological ProductsIBA 01/2022 - 02/2011
4	ErbB Receptors (EGF Receptor)IBA 01/2021 - 02/2003
4	MicroRNAs (MicroRNA)IBA 09/2020 - 12/2018
4	RNA (Ribonucleic Acid)IBA 01/2020 - 11/2016
4	Lysine (L-Lysine)FDA Link 07/2012 - 02/2011
3	PropionatesIBA 01/2022 - 03/2019
3	Histone-Lysine N-MethyltransferaseIBA 11/2021 - 10/2011
3	Monoclonal AntibodiesIBA 01/2020 - 02/2003
3	LigandsIBA 01/2020 - 02/2016
3	EnzymesIBA 08/2019 - 06/2002
3	Bromodeoxyuridine (BrdU)IBA 08/2013 - 05/2011
3	Small Interfering RNA (siRNA)IBA 08/2012 - 10/2011
2	Therapeutic UsesIBA 01/2021 - 01/2020
2	CateninsIBA 01/2021 - 11/2016
2	Long Noncoding RNAIBA 09/2020 - 12/2019
2	CytokinesIBA 01/2020 - 01/2017
2	Cetuximab (Erbitux)FDA Link 01/2020 - 02/2016
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2019 - 04/2014
2	sodium propionateIBA 08/2019 - 03/2019
2	HMGB1 Protein (HMG1)IBA 01/2016 - 09/2011
2	Phosphotransferases (Kinase)IBA 04/2014 - 10/2012
1	Neutralizing AntibodiesIBA 01/2022
1	VaccinesIBA 01/2022
1	SmokeIBA 01/2022
1	GoldIBA 08/2021
1	Hepatitis B Core AntigensIBA 08/2021
1	IonsIBA 08/2021
1	trovafloxacinIBA 05/2021
1	src-Family KinasesIBA 01/2021
1	Galectin 3 (LGALS3)IBA 01/2021
1	Betulinic AcidIBA 12/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2020
1	Messenger RNA (mRNA)IBA 12/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2020
1	Competitive Endogenous RNAIBA 09/2020
1	Circular RNAIBA 09/2020
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2020
1	Tight Junction ProteinsIBA 01/2020
1	Dextrans (Dextran)FDA Link 01/2020
1	Peroxidase (Myeloperoxidase)IBA 01/2020
1	MucinsIBA 01/2020
1	Panitumumab (Vectibix)FDA Link 01/2020
1	Hormones (Hormone)IBA 01/2020
1	Dextran SulfateIBA 01/2020
1	Interleukin-2 (IL2)IBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 12/2019
1	silmitasertibIBA 10/2019
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2019
1	Cytotoxins (Cytolysins)IBA 09/2019
1	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA 08/2019
1	SurvivinIBA 08/2019
1	Butyric Acid (Butanoic Acid)IBA 08/2019
1	Butyrates (Butyrate)IBA 08/2019
1	Volatile Fatty AcidsIBA 03/2019
1	human PRMT2 proteinIBA 03/2019
1	Propidium (Propidium Iodide)IBA 02/2019
1	Annexin A5IBA 02/2019

Therapy/Procedure

21	Therapeutics 08/2021 - 02/2003